Tuesday, February 11, 2014

History of sickle cell anemia

Sickle cell anemia is a hereditary disease that was discovered in 1910 though it had been present in Africa for several years. According to the Nemours Foundation sickle cell anemia was discovered by Dr. James B. Herrick; a cardiologist. A patient named Walter Clement came to him with complains of pain and pneumonia but Herrick assigned him to Dr. Ernest Irons because of his lack of interest his red blood cells had a shape of a sickle. Herrick became interested and published a paper naming the disease "sickle cell disease" which he became known for. A carrier has two blood types hemoglobin

    
S (sickle) and Hemoglobin A (normal). If the trait only has S then the person has sickle cell anemia.
If the parents have the disease then the genotype is SS but if they are a carrier the genotype is AS. If an individual does not have sickle cell anemia at all the genotype is AA
It's not chromosomal but hemoglobin abnormality

                    

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